Christof Koch's Biophysics of Computation: Information Processing in Single PDF

By Christof Koch

ISBN-10: 0195104919

ISBN-13: 9780195104912

ISBN-10: 0195181999

ISBN-13: 9780195181999

Neural community examine usually builds at the fiction that neurons are basic linear threshold devices, thoroughly neglecting the hugely dynamic and intricate nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: details Processing in unmarried Neurons demanding situations this suggestion, utilizing richly particular experimental and theoretical findings from mobile biophysics to provide an explanation for the repertoire of computational capabilities to be had to unmarried neurons. the writer exhibits how person nerve cells can multiply, combine, or hold up synaptic inputs and the way details may be encoded within the voltage around the membrane, within the intracellular calcium focus, or within the timing of person spikes.
Key themes lined comprise the linear cable equation; cable concept as utilized to passive dendritic timber and dendritic spines; chemical and electric synapses and the way to regard them from a computational viewpoint; nonlinear interactions of synaptic enter in passive and lively dendritic bushes; the Hodgkin-Huxley version of motion capability iteration and propagation; part house research; linking stochastic ionic channels to membrane-dependent currents; calcium- and potassium-currents and their position in info processing; the position of diffusion, buffering and binding of calcium, and different messenger platforms in details processing and garage; brief- and long term versions of synaptic plasticity; simplified versions of unmarried cells; stochastic features of neuronal firing; the character of the neuronal code; and unconventional types of sub-cellular computation.
Biophysics of Computation: details Processing in unmarried Neurons serves as a great textual content for complex undergraduate and graduate classes in mobile biophysics, computational neuroscience, and neural networks, and should attract scholars and pros in neuroscience, electric and laptop engineering, and physics.

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Biophysics of Computation: Information Processing in Single Neurons (Computational Neuroscience Series) by Christof Koch

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