By Mark C. Williams,III, L. James Maher
Depite the quick growth of the sphere of biophysics, there are only a few books that comprehensively deal with particular issues during this quarter. lately, the sector of unmarried molecule biophysics has built in a short time, and some books particularly treating unmarried molecule equipment are commencing to look. even though, the promise of unmarried molecule biophysics is to give a contribution to the certainty of particular fields of biology utilizing new equipment. This ebook could specialize in the categorical subject of the biophysics of DNA-protein interactions, and would come with using new techniques, together with either bulk tools in addition to unmarried molecule tools. this may make the ebook beautiful to someone operating within the basic quarter of DNA-protein interactions, that is after all a much broader marketplace than simply unmarried molecule biophysicists or perhaps biophysicists.
The topic of the e-book could be the biophysics of DNA-protein interactions, and should comprise new tools and effects that describe the actual mechanism through which proteins have interaction with DNA. for instance, there was a lot contemporary paintings at the mechanism during which proteins look for particular binding websites on DNA. a couple of chapters may be dedicated to experiments and idea that make clear this significant challenge. we are going to additionally hide proteins that adjust DNA homes to facilitate interactions vital for transcription or replication. one other component to the ebook will hide the biophysical mechanism during which motor proteins have interaction with DNA. eventually, we are going to disguise higher protein-DNA complexes, similar to replication forks, recombination complexes, DNA fix interactions, and their chromatin context.
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Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics, Biomedical Engineering) by Mark C. Williams,III, L. James Maher